BIOINFORMATICS TOOLS FOR GENE LIST ANALYSIS

MUHOVIĆ, Imer and BEŠIĆ, Larisa and AŠIĆ, Adna and DOGAN, Serkan and DOLUCA, Osman (2014) BIOINFORMATICS TOOLS FOR GENE LIST ANALYSIS. International Symposium on Sustainable Development. ISSN 978-9958-834-36-3

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Abstract

The advent of the era of high-throughput sequencing has brought a wealth of biological data to researchers, but the vastness of the available data has created a demand for tools that could be used to analyze it. One such type of tools are gene set analysis tools, that take a list of genes that were found to be up or down regulated during an experiment. For the sake of simplicity this review focuses solely on freely available web based tools that have been published or have undergone significant updates in the last 5 years. This review is meant to assist tool developers to better understand the needs of the end-users, and in it we look at the currently available gene list analysis tools, their strengths and weaknesses, and offer suggestions for their improvement. Key words: microarray, gene set, systems biology, enrichment, gene ontology

Item Type: Article
Subjects: Q Science > Q Science (General)
Q Science > QH Natural history > QH301 Biology
Q Science > QH Natural history > QH426 Genetics
Divisions: International Symposium on Sustainable Development
Depositing User: Mr. Edis Bulic
Date Deposited: 23 Jun 2014 13:43
Last Modified: 23 Jun 2014 13:43
URI: http://eprints.ibu.edu.ba/id/eprint/2450

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